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pentobarbital will lower the extent or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.Observe Carefully (1)mitotane decreases levels of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Mitotane is a robust inducer of cytochrome P-4503A4; check when coadministere